منابع مشابه
Mucosal healing and mortality in coeliac disease.
BACKGROUND Coeliac disease (CD), characterised by the presence of villous atrophy (VA) in the small intestine, is associated with increased mortality, but it is unknown if mortality is influenced by mucosal recovery. AIMS To determine whether persistent VA is associated with mortality in CD. METHODS Through biopsy reports from all pathology departments (n = 28) in Sweden, we identified 7648...
متن کاملMucosal ulceration and mesenteric lymphadenopathy in coeliac disease.
serum aLkaline phosphatase was 32 K.A. units/100 ml. These figures were strongly suggestive of neonatal rickets and maternal osteomalacia respectively.X-ray films of the infant's long bones showed evidence of active rickets, most noticeable at the lower femoral epiphyses (fig. 2). Emination of the urine showed generalized amino-aciduria. The infant was treated with 1,000 I.U. of calciferol dail...
متن کاملMucosal secretory IgA and secretory piece in adult coeliac disease.
Immunofluorescence studies with specific antisera to secretory IgA (11S IgA) and secretory piece were carried out on the jejunal mucosa of nine patients with adult coeliac disease (treated and untreated). The results were compared with those obtained in four normal patients and in four patients with local and systemic IgA (7S) deficiency. 11S IgA and secretory piece were localized to the upper ...
متن کاملTargeting mucosal healing in Crohn's disease.
The goal of medical treatment for Crohn's disease includes improving patients' quality of life while reducing the need for hospitalization and surgery. The current medical armamentarium includes 5-aminosalicylates, corticosteroids, immunomodulators, and biologic agents. In the past, response to treatment was measured by clinical improvement in symptoms; however, with the advent of disease-modif...
متن کاملImmunohistochemical analysis of mucosal gamma-interferon production in coeliac disease.
The role of gamma-interferon in the pathogenesis of enteropathies with an immunological basis such as coeliac disease, is unclear. Gamma-interferon immunoreactive lymphocytes were quantified in jejunal biopsies from patients with coeliac disease and from normal controls. In coeliac disease, there was an apparent decrease in the percentage of both intraepithelial (3.5% v 13.5%) and lamina propri...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2012
ISSN: 0269-2813
DOI: 10.1111/apt.12164